Hypertensive disorders of pregnancy (HDP) are a group of syndromes defined by the onset of hypertension during pregnancy with an incidence of 8–10% 1. This study provides data as a basis for interpregnancy care/counseling, but further research is necessary to validate our findings and confirm this relationship. An annual BMI increase of ≥ 1.0 kg/m 2/year was related to HDP development in subsequent pregnancies for women without a history of HDP. A history of HDP (aOR, 16.76 95% confidence interval, 9.62 − 29.22), and annual BMI gain (aOR, 2.30 95% CI, 1.76 − 3.01) were independent risk factors for HDP in subsequent pregnancies. This study included 1,746 pregnant women. The aORs in several annual BMI change categories were also calculated in the subgroups classified by HDP occurrence in the index pregnancy. A multicenter retrospective study of data from 2009 to 2019 examined the adjusted odds ratio (aOR) of HDP in subsequent pregnancies. This study aimed to clarify the association between annual BMI changes during the interpregnancy period and HDP risk in subsequent pregnancies. Therefore, we suggest considering the annual change in the body mass index (BMI). However, in interpregnancy care/counseling, the unpredictability of the timing of the next conception and the difficulties in preventing age-related body weight gain must be considered while setting weight management goals. Weight gain during interpregnancy period is related to hypertensive disorders of pregnancy (HDP).
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